Asst. Prof. Kiril Kirilov, PhD
Professional biography:
Гл. ас., д-р, инж. Кирил Тодоров Кирилов,
Образование:
2001 Магистър, Инженер Биотехнолог, Химикотехнологичен и металургичен университет, София
2014 „Доктор” по Молекулярна биология , 4.3. Биологически науки Институт по Молекулярна биология, Българска Академия на Науките
Месторабота:
2007-2022. Институт по Молекулярна биология, Българска Академия на Науките (ИМБ-БАН), Секция „Регулация на генната активност ”. Дисертационен труд на тема „Кодонова употреба при бактерии и животински митохондрии“
2022 -понастоящем - Нов Български университет. Главен асистент, департамент биологически науки,
Специализации:
2003 – Международен център по генетичен инженеринг и биотехнологии, Триест, Италия. Биоинформатика
2013 – Carleton University, Отава, Канада Биоинформатика
Publications:
Teodor Kirilov, Anastas Gospodinov & Kiril Kirilov (2023) An algorithm and application to efficiently analyse DNA fibre data, Biotechnology & Biotechnological Equipment, 37:1, DOI: 10.1080/13102818.2023.2206488
Kühl, T., Georgieva, M.G., Hübner, H., Imhof, D., Kirilov. K Tzvetkov, N.T.Neurotensin(8–13) analogs as dual NTS1 and NTS2 receptor ligands with enhanced effects on a mouse model of Parkinson's diseaseEuropean Journal of Medicinal Chemistrythis 2023, 254, 115386
Yeung, A.W.K., Choudhary, N., Tewari, D., Horbańczuk, J.O.,Kirilov. K.,Atanasov, A.G.Lycopene: total-scale literature landscape analysis of a valuable nutraceutical with numerous potential applications in the promotion of human and animal health. Animal Science Papers and Reportsthis link is disabled, 2022, 40(2), pp. 119–134
Handzhiyski Y, Tsekovska R, Kirilov K, Niwa T, Ivanov I, Mironova R. Enhancing effect of L-lysine on glycation of histone H1 and bovine serum albumin in vitro. A Closer Look at Glycation: A Potential Hotspot for Age-related Complications and Diseases, Nova Science Publishers., Inc, NY, USA, 2021, ISBN:978-1-53619-176-9, 19, 79-98
Tsekovska R, Kirilov K, Gatev E, Mironova R, Handzhyiski Y. Investigation of purine compounds for anti-glycation activity in vitro. Journal of Chemical Technology and Metallurgy, 57, 1, University of Chemical Technology and Metallurgy, 2022, ISSN:1314-7471 (print), 1314-7978 (on line), 19-24. SJR 0.22
Lazarova MI, Tsekova DS, Tancheva LP, Kirilov KT, Uzunova DN, Vezenkov LT, Tsvetanova ER, Alexandrova AV, Georgieva AP, Gavrilova PT, Dragomanova ST, Papazova MG, Handzhiyski YS, Kalfin RE. New Galantamine Derivatives with Inhibitory Effect on Acetylcholinesterase Activity. J Alzheimers Dis. 2021 Aug 16. doi: 10.3233/JAD-210577
Engibarov S, Tsekovska R, Kirilov K, Gatev E, Ivanov I, Mironova R, Handzhyiski Y. Deoxyribonuclease activity of allenic acids. Journal of chemical technology and Metallurgy, University of Chemical Technology and Metallurgy, 2021, ISSN:1314-7471 (print), 1314-7978
Andy Wai Kan Yeung, Maya G. Georgieva, Kiril Kirilov, Aneliya A. Balacheva, Martina I. Peeva, Olaf K. Horbanczuk, Jaroslaw O. Horbanczuk, Massimo Lucarini, Alessandra Durazzo, Antonello Santini, Eliana B. Souto, Tamara I. Pajpanova, Luigi Milella, Atanas G. Atanasov, Nikolay T. Tzvetkov (2020). Neurotensins and their therapeutic potential: Research field study. Future Med. Chem
K Kirilov, P Borovska, Conceptual model of integrated approach for in silico knowledge data discovery for breast cancer diagnostics and precision therapy, AIP Conference Proceedings 2172 (1), 020003
Rositsa Tsekovska, Yordan Handzhiyski, Elitsa Boteva, Kiril Kirilov, Toshimitsu Niwa, Ivan Ivanov, Roumyana Mironova. Advanced Glycation End Products in Escherichia coli KR12 – a Sign of Aging. In: Advanced Glycation End Products (AGEs): Regulation, Function and Role in Health and Disease. Nova Publishers, Inc. NY, USA, 2017
Kiril T Kirilov, Ivan G Ivanov, Ashkan Golshani. Termination codons and stop codon context in bacteria and mammalian mitochondria, Biotechnology Biotechnological Equipment. 27, 4, 2013, ISSN:ISSN: 1310R2818, DOI: 10.5504/BBEQ.2013.0052
Kiril Kirilov, Ivan G Ivanov. A programme for determination of codons and codons context frequency of occurrence in sequenced genomes. Biotechnology Biotechnological Equipment, 2012, ISSN:ISSN: 1310R2818, DOI: 10.5504/BBEQ.2012.0074.
B. Bachvarov, K. Kirilov, I. Ivanov. Codon usage in prokaryotes. Biotechnology Biotechnological Equipment, Taylor Francis, 2008, DOI: 10.1080/13102818.2008.10817533.
Popov M., Petrov S., Kirilov K., Nacheva G., Ivanov I. Segregational instability in E. coli of expression plasmids carrying human interferon gamma gene and its 3 Rend truncated variants. Biotechnology and Biotechnological Equipment, 23, 2, Taylor Francis, 2009, ISSN: 1310R2818 (Print), 1314R3530 (Online), 840R843, 2009.
V. Maximova, K. Kirilov, S. Markov, I. Ivanov “Comparative genomic studies of influenza A viruses performed on BlueGeneP supercomputer: Part 1. Conservative nucleotide sequences in influenza A virus genomes revealed by multiple sequence alignment”. Biotech. Biotechnol. Eq., 25, 2672R2678, 2011.
B. Bachvarov, K. Kirilov, I. Ivanov “Codon and codon pairs usage in bacteria”. In: Bacterial DNA, Chapter 1 (Knudsen, W.D. and Bruns, S.S., eds.), Nova Science Publishers, NY, USA (2010), pp. 3R49. ISBN 978R1R60741R094R2.
Patents:
1. K. Kirilov and I. Ivanov “A set of practical training in chemistry and environmental protection (VIII and IX course)” Patent No. BG 2017/2560 (25.07.2017). Учебни помагала и пособия по химия за средните училища
2. K. Kirilov and I. Ivanov A set of practical training in chemistry and environmental protection (X and XI course)” Patent No. BG 2017/2566 (25.07.2017). Учебни помагала и пособия по химия за средните училища
- Courses from the current semester:
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CELB065 Genetic engineering and GMO CELB090 Structural Biology CELB109 Chemistry for Biologists GENB093 History of Science VIRB404 Psychotropic Substances and Effects on Brain Activity VIRB502 Molecular Biology, Part 1 VIRB512 Project: Biochemistry VIRB811 Internship: Molecular-Biological Methods and GMOs VIRB813 Project: Human Genetics VIRB816 Statistical Methods for Processing Experimental Results